T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

The viral transposable element, MERVL, acts as a central switch during early embryonic development, driving totipotent gene ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

Understanding how these cells develop and function is like decoding a complex puzzle. "By perfecting stem cell methods that mimic the development of the normal blood stem cells found in our bodies we ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even ...

Developing bioassay methods requires a new approach for cell and gene therapy drug development. As cell-based methods continue to evolve in support of gene therapies to assess product potency through ...

Activation and expansion are essential for success in both autologous and allogeneic therapies. Gamma-delta (γδ) T cells make up on average 4–5% of T cells found in human peripheral blood (1). Two ...

Researchers suggest that MultiCell could potentially be used to discern early patterns of disease, such as in asthma.