T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

B cells were first characterized in the 1960s and early 1970s, when Max Cooper and Robert Good showed that surgical removal of the bursa of Fabricius (a primary immune organ in birds) rendered ...

Understanding how these cells develop and function is like decoding a complex puzzle. "By perfecting stem cell methods that mimic the development of the normal blood stem cells found in our bodies we ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Activation and expansion are essential for success in both autologous and allogeneic therapies. Gamma-delta (γδ) T cells make up on average 4–5% of T cells found in human peripheral blood (1). Two ...

Developing bioassay methods requires a new approach for cell and gene therapy drug development. As cell-based methods continue to evolve in support of gene therapies to assess product potency through ...

Researchers suggest that MultiCell could potentially be used to discern early patterns of disease, such as in asthma.

Scripps Research scientists find that certain gut bacteria are essential for building immune defenses during infancy, pointing to new strategies for protecting children’s health.