To enable cells to respond and adapt to their environment, they must be able to receive and process information (or "signals") that originate outside of the cell. Cell signaling – also sometimes ...

Our research focus is to understand the signalling and metabolic networks that are related to cell growth and malignant transformation. We aim to explore unique metabolic nodes for novel therapeutic ...

Dr Sebastian Guettler’s group is researching the ways in which certain enzymes, known as ADP-ribosyltransferases (ARTs), control cell function. Professor Sebastian Guettler is Deputy Head of the ...