The field of protein production is seeing widespread adoption of cell-free protein synthesis (CFPS), revolutionising the industry with its high-throughput and cost-effective capabilities. This ...
Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
At the recent ELRIG Drug Discovery conference, Technology Networks<i/> spoke with Dr. Kundan Sharma to learn more about how cell-free expression platforms are transforming membrane protein research.
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How Cells Balance Their Protein Levels
EPFL researchers have discovered how cells help keep their protein levels steady even when their ability to make new proteins ...
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Super-probiotic bacteria created through ribosomal engineering
Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
Higher Gene expression Protein synthesis Gene expression is the process by which specific genes are activated to produce a required protein. The process is made up of the transcription and translation ...
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Cellular Energy Sensors Dual Roles in Alzheimers Unveiled
The catalytic α subunit of AMPK exists in two isoforms, α1 and α2, encoded by distinct genes. While these isoforms share ...
The FDA approval of denileukin diftitox (Lymphir) marked a significant shift in this paradigm. As a first-in-class immunotoxin, it employs a dual-action mechanism: directly targeting interleukin-2 (IL ...
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