Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...
Next-generation sequencing (NGS) technologies, used to rapidly read genetic information, have consistently opened new frontiers in biology. The first NGS device – 454 Life Sciences’ Genomic Sequencer ...
Noncoding elements in the genome, such as enhancers, silencers, and insulators, play important roles in gene expression and thus cellular behavior. Therefore, these elements may be of particular ...
Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...
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Scientists identify a non-coding gene that directly controls how big cells grow
The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...
But only a tiny percentage of our DNA – around 2% – contains our 20,000-odd genes. The remaining 98% – long known as the non-coding genome, or so-called ‘junk’ DNA – includes many of the switches that ...
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