C5b initiates the membrane attack pathway, which results in the membrane attack complex (MAC), consisting of C5b, C6, C7, C8, and polymeric C9. MAC is the cytolytic endproduct of the complement ...
The complement system is a central component of innate immunity, consisting of a large family of plasma and membrane bound proteins that are critical for protection against bacterial infection and ...
Pore-forming toxins (PFTs) are a diverse class of proteins capable of disrupting cell membranes through the formation of transmembrane channels. These molecular machines play a central role in both ...
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