Researchers have identified mutations in a set of proteins that predispose their carriers to preeclampsia, a complication that shows up in between 5 percent and 10 percent of pregnancies. Their work ...

The complement system, a pivotal element of antiviral immunity, is a cascade of proteins found in the bloodstream and at mucosal sites, such as the respiratory tract. Activated through three different ...

Immunotherapy is increasingly becoming standard therapy in cancer, with technology, such as checkpoint inhibitors and cell therapy, raising the efficacy bar in many forms of the disease. But the ...

Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement ...

Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...

Immunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. While much focus has been on engaging T-cells for fighting cancer, less attention has been ...

One can acquire humoral immunity to a specific infection or disease if administered with antibodies from someone who was previously been exposed to the same infection, circumventing the humoral ...

Suggested remit: To appraise the clinical and cost effectiveness of pegcetacoplan within its marketing authorisation for treating primary complement 3 (C3) glomerulopathy and primary immune-complex ...

Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...