Wet granulation, dry granulation and direct blending are the most popular granulation processes for solid dosage form manufacture in the pharmaceutical industry, but they each have distinct drawbacks.

Advanced dynamic process control of a fluid-bed granulation process using PAT data improves product quality. Globally, there is an increasing trend toward the use of Industry 4.0 principles, with the ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Granulation is important in the pharmaceutical industry because of increased pressures due to the costs of manufacturing solid dosage forms. Granulation forms coarser collections from fine powder.