Sometimes a replicating cell must choose the lesser of two evils. For example, when a replicating cell is stressed, it may struggle to pair bases against its single-stranded DNA (ssDNA) template, even ...
The cells that make up our body are tiny, each of them measuring only micrometers in diameter. The ensemble of chromosomal DNA molecules that encode the genome, on the other hand, measures almost 2 ...
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently ...
In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, PhD ...
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DNA from the mother and father are handled differently in the newly formed embryo, researchers discover
Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in their development. New insights into how maternal and paternal DNA is ...
Each replicated chromosome is made up of two identical strands called chromatids that are joined together. Each chromatid is a full length DNA molecule. The stages outlined in the following example ...
Researchers have discovered how a key function of the AND-1 protein helps protect nascent DNA strands from degradation. Researchers from Tokyo Metropolitan University and the FIRC Institute of ...
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