Why? The human proteome is extremely diverse. Whilst the genome is essentially constant across different cell populations in the human body (bar a few exceptions), in order for individual cells to ...
Dr Jörg Mansfeld's group investigates how protein modifications by ubiquitin and redox systems ensure cell homeostasis and how aberrations in both systems are linked to proliferation and tumorigenesis ...
Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...
A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...
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