Quantifying the risk of cancer associated with pathogenic mutations in germline cancer susceptibility genes—that is, penetrance—enables the personalization of preventive management strategies.

Though it remains a common practice, requiring patients to have nothing by mouth (NPO) for several hours before percutaneous cardiovascular procedures doesn’t appear to have any advantages over ...

Meta-analysis is an objective examination of published data from many studies of the same research topic identified through a literature search. Through the use of rigorous statistical methods, it can ...

Network meta-analysis (NMA) is a method that pools evidence from randomised controlled trials that compare two or more interventions, but where each trial may compare different interventions. NMA ...

The peer-reviewed Annals of Surgery published a meta-analysis of 30-day surgical outcomes across seven oncological surgical procedures, comparing robotic, laparoscopic, and open surgical approaches.

TSD 20: Multivariate meta-analysis of summary data for combining treatment effects on correlated outcomes and evaluating surrogate endpoints (PDF, 1.2MB) – October 2019 – Updated December 2022: ...

Objective To estimate the dose–response associations between non-occupational physical activity and several chronic disease and mortality outcomes in the general adult population. Design Systematic ...