Testing drugs before they reach human trials typically involves the use of animal models. For decades, mice have been one of the most established preclinical models. However, these “inbred” strains ...

Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

For more than a century, Alzheimer’s disease has been framed as irreversible. Once memory and thinking decline, recovery has ...