The sequencing of the first human genome in 2003 marked a major milestone in molecular biology. In the years since, it has become apparent that the human proteome – the collection of proteins that are ...

Post-translational modification (PTM) is the covalent and generally enzymatic modification of proteins following protein biosynthesis. Proteins are synthesized by ribosomes that translate mRNA into ...

What is Post-Translational Modification of Proteins? Post-translational modification of proteins is a covalent process that a protein goes through during or after translation. This process changes the ...

Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

The amino acid side chains of proteins undergo various post-translational modifications (PTMs) which significantly impact protein function and mediate complex cellular events. Measuring the dynamics, ...

Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.

At the University of Oxford, scientists have developed a nanopore technology that can identify three different post-translational modifications (PTMs) in individual proteins, even deep within long ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

One of the first things that students learn when they enter a biology class is the central dogma: DNA → messenger RNA → proteins. Only about 3% of the human genome directly codes for proteins, which ...