The sequencing of the first human genome in 2003 marked a major milestone in molecular biology. In the years since, it has become apparent that the human proteome – the collection of proteins that are ...
Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...
Post-translational modification (PTM) is the covalent and generally enzymatic modification of proteins following protein biosynthesis. Proteins are synthesized by ribosomes that translate mRNA into ...
Dr Jörg Mansfeld's group investigates how protein modifications by ubiquitin and redox systems ensure cell homeostasis and how aberrations in both systems are linked to proliferation and tumorigenesis ...
Protein phosphorylation is one of the most important post-translational modifications of proteins, and phosphorylation occurs in about 1/3 of all proteins in eukaryotic cells. Catalyzed by protein ...
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...
A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...
The recent Strasburger Hot Topic Symposium on "Co- and Post-translational Control in Chloroplasts" was held at the University of Münster in November 2024. It brought together more than 50 researchers ...
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