Nature

Universal strategies in research and drug discovery based on protein-fragment complementation assays

Protein-fragment complementation assays (PCAs) provide a general methodology to detect and study spatial and temporal dynamics of protein–protein interactions in intact living cells and have many ...
Nature

β-Lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein–protein interactions

Technical Report Published: 01 June 2002 β-Lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein–protein interactions André Galarneau, Martin Primeau, Louis-Eric ...