Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity.

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

For several years, researchers in Würzburg have been using state-of-the-art single-cell analysis to study individual cells.

Neoantigen vaccines are at the forefront of cancer research, driving personalized immunotherapy and improving outcomes ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...