More than 80 percent of all drug candidates in the pharma R&D suffer from poor solubility and are therefore rejected early in the drug discovery process. Now researchers show that a new material, ...
About 40% of marketed drugs are thought to be poorly water soluble. Development efforts might have to be redoubled, however, because between 70 and 90% of drug candidates in the pipeline are believed ...
High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...
An analysis of the approaches and tools used to tackle the problem of poorly soluble drugs. Improving the solubility of poorly water-soluble drugs is of crucial importance. As the number and diversity ...
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