But if we want people to be healthy in old age we have to understand the mechanisms underlying the deterioration of our bodies over time. Doing so – and learning how we can prevent it – has been the ...

Discovery of the first molecular mechanism of action for a small molecule that improves RNA splicing in cells could lead to new therapeutics for the genetic disorder spinal muscular atrophy (SMA) and ...

Splicing of SMN2 generally skips exon 7, resulting in the production of a truncated and inactivated form of the SMN protein. NVS-SM1, a new compound reported by Palacino and colleagues, facilitates ...

PITTSBURGH, Pa., Dec. 16, 2020 (GLOBE NEWSWIRE) -- NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology company accelerating the genetic revolution using a new class ...

Image: Structure of the antitumor compound spliceostatin A (purple and orange) bound to a spliceosome complex (light blue and pink). Credit: Professor Vlad Pena. A team of scientists has created a ...

A compound already used to treat pneumonia could become a new therapy for an inherited muscular wasting disease, according to researchers at the University of Oregon and the University of Rochester ...