Ribonucleotide reductases (RNRs) play a crucial role in cells as the only source of the building blocks needed for DNA replication and repair. They use radical-based chemistry to catalyze the ...

Researchers at Stockholm University have applied advanced electron microscopy techniques to finally unveil the structure of the widely used and century-old active pharmaceutical ingredient bismuth ...

Elimination of the 5′ cap of eukaryotic mRNAs, known as decapping, is considered to be a crucial, irreversible and highly regulated step required for the rapid degradation of mRNA by Xrn1, the major ...

Telomerase contains a large RNA subunit, TER, and a protein catalytic subunit, TERT. Whether telomerase functions as a monomer or dimer has been a matter of debate. Here we report biochemical and ...

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. Fidelity International, a bastion of the active management industry, issued a “game-changer” challenge to ...

If you’ve ever put cash into an exchange-traded fund (ETF), it is likely to have been a passive investment: a fund that tracks a particular stock market index up and down, rather than actively trying ...