Imagine you’re working at a laboratory that creates pharmaceuticals. You figure out the reactants and the chemistry involved to make a new drug. You design a production line, and your new factory ...
Raman spectroscopy is used to characterize materials by analyzing molecular or crystal rotations and vibrations that are excited by a laser, and exhibit vibrations that are specific to the molecules ...
Pharmaceutical compounds often crystallize in a variety of forms known as polymorphs. Because of differences in stability, solubility, and other properties that affect the molecules’ behavior in the ...
In this interview, Dr. Matteo Daldosso, Physical Properties Unit manager at Aptuit and Dr. Sebastian Wegner, Product Manager of Solid-state NMR at Bruker Biospin, discuss novel solutions for solid ...
Polymorphism is observed in most active pharmaceutical ingredients (APIs), due to the different forms or molecular structures of a compound affecting the efficacy, stability or bio-availability of the ...
Researchers explored a colloidal crystal model to produce specific polymorphs, required for use in materials science and pharmaceuticals. Polymorphs are not mythical, chimeric beasts -- they are ...
Gauging the adequate level and type of screening is the challenge when identifying relevant crystalline forms. Solid-dosage drugs remain the preferred dosage form due to ease of administration and ...
This image by Shaista Hassan Lone, a scientist at the University of Kashmir, shows two polymorphs—different crystal structures—of 4-(dimethylamino)benzaldehyde. When Lone initially set out to grow ...
The authors propose extending initial solvent screening for a single-solvent system to the cocktail solvent screening of binary and ternary solvent mixtures. Crystallization from solutions is not only ...
MADISON, Wis.--(BUSINESS WIRE)--Breakthrough research has now revealed the true crystal forms of pharmaceutical psilocybin. A new study overcomes experimental challenges to solve the crystallographic ...