St. Jude Children’s Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia ...
Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...
Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...
Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...
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Scientists identify a non-coding gene that directly controls how big cells grow
The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...
Noncoding elements in the genome, such as enhancers, silencers, and insulators, play important roles in gene expression and thus cellular behavior. Therefore, these elements may be of particular ...
These genes are part of the non-coding genome, which makes up about 98% of our DNA and was long dismissed as “junk.” This new ...
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...
It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...
(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...
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