Why? The human proteome is extremely diverse. Whilst the genome is essentially constant across different cell populations in the human body (bar a few exceptions), in order for individual cells to ...

What is Post-Translational Modification of Proteins? Post-translational modification of proteins is a covalent process that a protein goes through during or after translation. This process changes the ...

Post-translational modification (PTM) is the covalent and generally enzymatic modification of proteins following protein biosynthesis. Proteins are synthesized by ribosomes that translate mRNA into ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Previous work showed that histone ‘readers’, which bind to post-translational modifications on histones, may be upregulated in melanoma and thereby upregulate oncogenes. Given that the histone reader ...