The origins of modern structural biology date back to the 1910s, when the German physicist Max von Laue discovered that biological crystal samples irradiated with X-rays produced diffraction patterns ...
Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...
Giving Structure to Language: Profluent’s AI Models Move toward Precise and Steerable Protein Design
The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...
Basecamp Research says it has augmented the AlphaFold2 artificial intelligence tool for predicting protein structures to create a platform that is more accurate and better at modelling small-molecule ...
Single-structure models derived from X-ray data do not adequately account for the inherent, functionally important dynamics of protein molecules. We generated ensembles of structures by time-averaged ...
The rapid advancement of AI-powered tools, such as RoseTTAFold and AlphaFold, has revolutionised protein structure prediction, creating exciting opportunities across drug discovery and structural ...
Google DeepMind's AI model for predicting the structures of proteins and other biological molecules, AlphaFold 3, has been implemented in an open source manner and the ongoing research project has ...
Professor Jonathan Wittenberg used this model of sperm whale myoglobin structure as a teaching tool at the Albert Einstein College of Medicine at Yeshiva University in the Bronx. It was used beginning ...
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