PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...

Researchers have found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared with that from normal controls. Specifically, methylation levels ...

Scientists have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. Previously, microRNAs were mainly thought to be found in cytoplasm. The ...

The authors provide further insight into microRNA biology, and the simplicity of anti-miR oligonucleotide drug delivery. RNA-based therapeutics hold significant potential as promising treatment ...

Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor today. Victor R. Ambros, PhD, and Gary ...

When the entire human genome was first sequenced 13 years ago, scientists were shocked by how little our DNA varied from our animal cousins. In fact, there was just 1.2 per cent difference. Now a new ...

In the October15th issue of G&D, Dr. Fen-Biao Gao and colleagues at UCSF report that microRNA-9a (mir-9a) regulates neural development in the fruit fly, Drosophila. Using loss-of-function analysis, Dr ...

A research team from the University of Eastern Finland and the University of Oxford says it has shown that small RNA molecules occurring naturally in cells, i.e., microRNAs, are also abundant in cell ...

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression by interacting with messenger RNAs (mRNAs) from genes that encode proteins. The aberrant expression of miRNAs has ...