Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within the nucleus, serve as central hubs for pre-mRNA 3′ end processing. This ...

Our group focuses on the structural basis of human pre-mRNA processing, including: splicing modulation by compounds with antitumour properties, ubiquitination in splicing and DNA repair and helicases.

Takara Bio Europe (TBE) announced the launch of new High Quality (HQ) grade mRNA production enzymes "T7 RNA polymerase, HQ" and "Pyrophosphatase (inorganic), HQ" suitable for pre-clinical and process ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

This article provides an overview of solutions to address key challenges facing vaccine developers or CDMOs wishing to build their own commercial-scale mRNA production facilities. Messenger RNA (mRNA) ...